CRISPR – Blood Cancer Genomics

CRISPR-Cas9 Genome Editing

by Charles Bell on April 9, 2015 with No Comments

CRISPR-Cas9 genome editing is a revolutionary technology that allows rapid and precise modification of the eukaryotic genome. Developed in 2013, the technology has exploded, with over 1000 published articles using the technology. Given the simplicity and efficiency of the technology, our … Read More

Understanding the Regulation of Early Mouse Embryonic Development

by Charles Bell on April 9, 2015 with No Comments

In this project theme, our lab is interested in understanding how normal mouse embryonic development is regulated by both transcription factors and long non coding RNAs. Using embryonic stem cells and embryoid body differentiation, a common model of early mouse development, … Read More