Ilsley, Melissa D; Gillinder, Kevin R; Magor, Graham W; Huang, Stephen; Bailey, Timothy L; Crossley, Merlin; Perkins, Andrew C. “Krüppel-like factors compete for promoters and enhancers to fine-tune transcription” Nucleic Acids Research (2017). 45:11:6572–6588. https://doi.org/10.1093/nar/gkx441
Gillinder, Kevin R; Tuckey, Hugh; Bell, Charles C; Magor, Graham W; Huang, Stephen; Ilsley, Melissa D; Perkins, Andrew C. “Direct targets of pSTAT5 signalling in erythropoiesis“. PloS one (2017). 12:7-e0180922. https://doi.org/10.1371/journal.pone.0180922
Arulogun, Suzanne O; Choong, Hock-Lai; Taylor, Debbie; Ambrosoli, Paula; Magor, Graham; Irving, Ian M; Keng, Tee-Beng; Perkins, Andrew C. “JAK1 somatic mutation in a myeloproliferative neoplasm“. Haematologica (2017). 102:8:e324-e327. http://dx.doi.org/10.3324/haematol.2017.170266
Mesa, Ruben A; Vannucchi, Alessandro M; Mead, Adam; Egyed, Miklos; Szoke, Anita; Suvorov, Aleksandr; Jakucs, Janos; Perkins, Andrew; Prasad, Ritam; Mayer, Jiri. “Pacritinib versus best available therapy for the treatment of myelofibrosis irrespective of baseline cytopenias (PERSIST-1): an international, randomised, phase 3 trial“. The Lancet Haematology (2017). http://dx.doi.org/10.1016/S2352-3026(17)30027-3
Ho, P Joy; Bajel, Ashish; Burbury, Kate; Dunlop, Lindsay; Durrant, Simon; Forsyth, Cecily; Perkins, Andrew C; Ross, David M. “A case‐based discussion of clinical problems in the management of patients treated with ruxolitinib for myelofibrosis“. Internal Medicine Journal 47:3-262-268 (2017). http://dx.doi.org/10.1111/imj.13341
Planutis, Antanas; Xue, Li; Trainor, Cecelia D; Dangeti, Mohan; Gillinder, Kevin; Siatecka, Miroslawa; Nebor, Danitza; Peters, Luanne L; Perkins, Andrew C; Bieker, James J; “Neomorphic effects of the neonatal anemia (Nan-Eklf) mutation contribute to deficits throughout development“. Development 144:3:430-440 (2017). Oxford University Press for The Company of Biologists Limited. http://dx.doi.org/10.1242/dev.145656
Lackey, Alan; Laing, Barbara; Perkins, Andrew; Bryant, Michael. “Diagnosis in subdural myeloid sarcoma” The Neuroradiology Journal 1971400916689340 (2017). http://dx.doi.org/10.1177/1971400916689343
Promiscuous DNA-binding of a mutant zinc finger protein corrupts the transcriptome and diminishes cell viability.
Kevin R. Gillinder, Melissa D. Ilsley, Danitza Nébor, Ravi Sachidanandam, Mathieu Lajoie, Graham W. Magor, Michael R. Tallack, Timothy Bailey, Michael J. Landsberg, Joel Mackay, Michael W. Parker, Luke A. Miles, Joel H. Graber, Luanne L. Peters, James J. Bieker and Andrew C. Perkins. Nucleic Acids Research Advance Access published November 28, 2016. doi:10.1093/nar/gkw1014
Andrew Perkins, Xiangmin Xu, Douglas R. Higgs, The KLF1 Consensus Workgroup, George P. Patrinos, Lionel Arnaud, James J. Bieker and Sjaak Philipsen. “Kruppeling Erythropoiesis: The increasing importance of DNA sequencing in human genetic disease illustrated by variants of a master regulator of erythropoiesis.” Blood (2016) 127(15):1856-62
Jacobsen R, Perkins AC and Levesque J-P. “Macrophages and regulation of erythropoiesis.” Current Opinion in Hematology (2015) 22(3):212-9.
Graham W. Magor, Michael R. Tallack, Nathan M. Klose, Debbie Taylor, Darren Korbie, Peter Mollee, Matt Trau and Andrew C. Perkins. “Rapid molecular profiling of myeloproliferative neoplasms using targeted exon re-sequencing of 86 genes involved in JAK-STAT signalling and epigenetic regulation.” Journal of Molecular Diagnostics (2016) Sep; 18(5):707-18
Max Gulhane, Lydia Murray, Ran Wang, Hui Ton, Jakob Begun, Graham Magor, Tim Florin, Andrew Perkins, Michael McGuckin and Sumaira Hasnain. “High fat diet and the colonic mucus barrier: Implications for Obesity and Inflammatory Bowel Disease.” Scientific Reports (2016) Jun 28; 6:28990
Charles C. Bell, Paulo P. Amaral, Anton Kalsbeek, Graham W. Magor, Kevin R. Gillinder, Pierre Tangermann, Lorena di Lisio, Seth W. Cheetham, Franziska Gruhl, Jessica Frith, Michael R. Tallack, Ke-Lin Ru, Joanna Crawford, John S. Mattick, Marcel E. Dinger, and Andrew C. Perkins. “The Evx1/Evx1as gene locus regulates anterior-posterior patterning during gastrulation. ” Scientific Reports (2016) May 26; 6:26657.
Kaur, Simranpreet, Liza J. Raggatt, Rebecca Jacobsen, Susan Millard, Valerie Barbier, Bianca Nowlan, Ingrid G. Winkler et al. “Autologous haematopoietic stem cell transplantation requires recipient BM macrophages.” Experimental Hematology 43, no. 9 (2015): S71.
Magor, Graham W., Michael R. Tallack, Kevin R. Gillinder, Charles C. Bell, Naomi McCallum, Bronwyn Williams, and Andrew C. Perkins. “KLF1 null neonates display hydrops fetalis and a deranged erythroid transcriptome.” Blood (2015): blood-2014.
Sorolla, Anabel, Michael R. Tallack, Harald Oey, Sarah K. Harten, Lucia Clemens-Daxinger, Graham W. Magor, Alex N. Combes, Melissa Ilsley, Emma Whitelaw, and Andrew C. Perkins. “Identification of novel hypomorphic and null mutations in Klf1 derived from a genetic screen for modifiers of α-globin transgene variegation.” Genomics 105, no. 2 (2015): 116-122.
Bell, Charles C., Graham W. Magor, Kevin R. Gillinder, and Andrew C. Perkins. “A high-throughput screening strategy for detecting CRISPR-Cas9 induced mutations using next-generation sequencing.” BMC genomics 15, no. 1 (2014): 1002.
Wang, Xunde, Laurel Mendelsohn, Heather Rogers, Susan Leitman, Nalini Raghavachari, Yanqin Yang, Yu Ying Yau et al. “Heme-bound iron activates placenta growth factor in erythroid cells via erythroid Krüppel-like factor.” Blood 124, no. 6 (2014): 946-954.
Pattabiraman, Diwakar R., Crystal McGirr, Konstantin Shakhbazov, Valerie Barbier, Keerthana Krishnan, Pamela Mukhopadhyay, Paula Hawthorne et al. “Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia (AML) by human AML oncogenes.” Blood 123, no. 17 (2014): 2682-2690.
Funnell, Alister PW, Ka Sin Mak, Natalie A. Twine, Gregory J. Pelka, Laura J. Norton, Tania Radziewic, Melinda Power et al. “Generation of mice deficient in both KLF3/BKLF and KLF8 reveals a genetic interaction and a role for these factors in embryonic globin gene silencing.” Molecular and cellular biology 33, no. 15 (2013): 2976-2987.
Tallack, Michael R., Graham W. Magor, Benjamin Dartigues, Lei Sun, Stephen Huang, Jessica M. Fittock, Sally V. Fry, Evgeny A. Glazov, Timothy L. Bailey, and Andrew C. Perkins. “Novel roles for KLF1 in erythropoiesis revealed by mRNA-seq.” Genome research 22, no. 12 (2012): 2385-2398.
Kovacevic, Igor, Jiong Hu, Ann Siehoff‐Icking, Nils Opitz, Aliesha Griffin, Andrew C. Perkins, Alan L. Munn et al. “The F‐BAR protein NOSTRIN participates in FGF signal transduction and vascular development.” The EMBO journal 31, no. 15 (2012): 3309-3322.
Sun, Lei, Zhihua Zhang, Timothy L. Bailey, Andrew C. Perkins, Michael R. Tallack, Zhao Xu, and Hui Liu. “Prediction of novel long non-coding RNAs based on RNA-Seq data of mouse Klf1 knockout study.” BMC bioinformatics 13, no. 1 (2012): 331.
Funnell, Alister PW, Laura J. Norton, Ka Sin Mak, Jon Burdach, Crisbel M. Artuz, Natalie A. Twine, Marc R. Wilkins et al. “The CACCC-binding protein KLF3/BKLF represses a subset of KLF1/EKLF target genes and is required for proper erythroid maturation in vivo.” Molecular and cellular biology 32, no. 16 (2012): 3281-3292.
Van Zuylen, Wendy J., Valerie Garceau, Adi Idris, Kate Schroder, Katharine M. Irvine, Jane E. Lattin, Dmitry A. Ovchinnikov et al. “Macrophage activation and differentiation signals regulate schlafen-4 gene expression: evidence for Schlafen-4 as a modulator of myelopoiesis.” PloS one 6, no. 1 (2011): e15723.
Tallack, Michael R., Tom Whitington, Wai Shan Yuen, Elanor N. Wainwright, Janelle R. Keys, Brooke B. Gardiner, Ehsan Nourbakhsh et al. “A global role for KLF1 in erythropoiesis revealed by ChIP-seq in primary erythroid cells.” Genome research 20, no. 8 (2010): 1052-1063.
Tallack, Michael R., and Andrew C. Perkins. “Megakaryocyte-erythroid lineage promiscuity in EKLF null mouse blood.” haematologica 95, no. 1 (2010): 144-147.
Papathanasiou, Peter, Robert Tunningley, Diwakar R. Pattabiraman, Ping Ye, Thomas J. Gonda, Belinda Whittle, Adam E. Hamilton, Simon O. Cridland, Rohan Lourie, and Andrew C. Perkins. “A recessive screen for genes regulating hematopoietic stem cells.” Blood 116, no. 26 (2010): 5849-5858.
Tallack, Michael R., Janelle R. Keys, Patrick O. Humbert, and Andrew C. Perkins. “EKLF/KLF1 controls cell cycle entry via direct regulation of E2f2.” Journal of Biological Chemistry 284, no. 31 (2009): 20966-20974.
Tallack, Michael, Thomas Whitington, Brooke Gardiner, Eleanor Wainwright, Janelle Keys, Marion Monet, Ehsan Nourbakhsh et al. “Klf1 regulatory networks in primary erythroid cells.” In Blood, vol. 114, no. 22, pp. 591-591. American Society of Hematology, 2009.
Amaral, Paulo P., Christine Neyt, Simon J. Wilkins, Marjan E. Askarian-Amiri, Susan M. Sunkin, Andrew C. Perkins, and John S. Mattick. “Complex architecture and regulated expression of the Sox2ot locus during vertebrate development.” Rna 15, no. 11 (2009): 2013-2027.
Kassahn, Karin S., Vinh T. Dang, Simon J. Wilkins, Andrew C. Perkins, and Mark A. Ragan. “Evolution of gene function and regulatory control after whole-genome duplication: comparative analyses in vertebrates.” Genome Research 19, no. 8 (2009): 1404-1418.
Whitington, Tom, Andrew C. Perkins, and Timothy L. Bailey. “High-throughput chromatin information enables accurate tissue-specific prediction of transcription factor binding sites.” Nucleic acids research 37, no. 1 (2009): 14-25.
Cridland, Simon O., Janelle R. Keys, Peter Papathanasiou, and Andrew C. Perkins. “Indian hedgehog supports definitive erythropoiesis.” Blood Cells, Molecules, and Diseases 43, no. 2 (2009): 149-155.
Keys, Janelle R., Michael R. Tallack, Ye Zhan, Peter Papathanasiou, Christopher C. Goodnow, Karin M. Gaensler, Merlin Crossley, Job Dekker, and Andrew C. Perkins. “A mechanism for Ikaros regulation of human globin gene switching.” British journal of haematology 141, no. 3 (2008): 398-406.
Cloonan, Nicole, Alistair RR Forrest, Gabriel Kolle, Brooke BA Gardiner, Geoffrey J. Faulkner, Mellissa K. Brown, Darrin F. Taylor et al. “Stem cell transcriptome profiling via massive-scale mRNA sequencing.” Nature methods 5, no. 7 (2008): 613-619.
Dinger, Marcel E., Paulo P. Amaral, Tim R. Mercer, Ken C. Pang, Stephen J. Bruce, Brooke B. Gardiner, Marjan E. Askarian-Amiri et al. “Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiation.” Genome research 18, no. 9 (2008): 1433-1445.
Sue, Nancy, Briony HA Jack, Sally A. Eaton, Richard CM Pearson, Alister PW Funnell, Jeremy Turner, Robert Czolij et al. “Targeted disruption of the basic Krüppel-like factor gene (Klf3) reveals a role in adipogenesis.” Molecular and cellular biology 28, no. 12 (2008): 3967-3978.
Wilkins, Simon J., Simon Yoong, Heather Verkade, Takamasa Mizoguchi, Sarah J. Plowman, John F. Hancock, Yutaka Kikuchi, Joan K. Heath, and Andrew C. Perkins. “Mtx2 directs zebrafish morphogenetic movements during epiboly by regulating microfilament formation.” Developmental biology 314, no. 1 (2008): 12-22.
Tallack, Michael R., Janelle R. Keys, and Andrew C. Perkins. “Erythroid Kruppel-like Factor Regulates the G1 Cyclin Dependent Kinase Inhibitor p18 INK4c.” Journal of molecular biology 369, no. 2 (2007): 313-321.
Funnell, Alister PW, Christopher A. Maloney, Lucinda J. Thompson, Janelle Keys, Michael Tallack, Andrew C. Perkins, and Merlin Crossley. “Erythroid Krüppel-like factor directly activates the basic Krüppel-like factor gene in erythroid cells.” Molecular and cellular biology 27, no. 7 (2007): 2777-2790.
Bruce, Stephen J., Robert W. Rea, Anita L. Steptoe, Meinrad Busslinger, John F. Bertram, and Andrew C. Perkins. “In vitro differentiation of murine embryonic stem cells toward a renal lineage.” Differentiation 75, no. 5 (2007): 337-349.
Pearson, R., A. P. W. Funnell, A. Kwok, J. Keys, M. Tallack, D. Hodge, A. C. Perkins, and M. Crossley. “The regulation of gene repression by BKLF.” Blood Cells, Molecules, and Diseases 38, no. 2 (2007): 133-134.
Perkins, Andrew C., Janelle R. Keys, Denise J. Hodge, and Michael R. Tallack. “Erythroid Kruppel-Like Factor Regulates E2F4 and the G1 Cdk Inhibitor, p18.” In ASH Annual Meeting Abstracts, vol. 106, no. 11, p. 1357. 2005.
Funnell, A. P. W., J. Keys, M. Tallack, D. Hodge, A. C. Perkins, and M. Crossley. “Identification of a novel, erythroid BKLF promoter.” Blood Cells, Molecules, and Diseases 38, no. 2 (2007): 139-140.
Keys, Janelle R., Michael R. Tallack, Denise J. Hodge, Simon O. Cridland, Rakesh David, and Andrew C. Perkins. “Genomic organisation and regulation of murine alpha haemoglobin stabilising protein by erythroid Kruppel‐like factor.” British journal of haematology 136, no. 1 (2007): 150-157.
Perkins, Andrew C., Michael Tallack, Ye Zhan, Peter Papathanasiou, Crhistopher Goodnow, Karin Gaensler, Paul M. Crossley, Job Dekker, and Janelle R. Keys. “Ikaros Drives Human Haemoglobin Switching by Facilitating Active Chromatin Hub Formation.” In ASH Annual Meeting Abstracts, vol. 110, no. 11, p. 1772. 2007.
Bruce, S., L. Rossiter, A. Steptoe, J. Deare, S. Ricardo, E. Naim, J. F. Bertram, and A. C. Perkins. “Kidney gene expression within mouse embryonic stem cells.” In Cytometry Part a, vol. 69, no. 5, pp. 415-415. Wiley-Liss, 2006.
van Vliet, Jane, Linda A. Crofts, Kate GR Quinlan, Robert Czolij, Andrew C. Perkins, and Merlin Crossley. “Human KLF17 is a new member of the Sp/KLF family of transcription factors.” Genomics 87, no. 4 (2006): 474-482.